Certificate of Analysis
| Product Name: | Embelin |
| Catalog Number: | M5611 |
| CAS Number: | 550-24-3 |
Physical and Chemical Properties
| Formula: | C17H26O4 |
| Molecular Weight: | 294.39 |
| Solubility: | DMSO ≥ 40 mg/mL |
| Storage: | 2-8°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Embelin is a cell-permeable benzoquinone compound that exhibits antitumor properties. Specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50 = 4.1 uM in a competitive binding assay with Smac peptide). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |