Certificate of Analysis

 

Product Name: Camptothecin
Catalog Number: M2199
CAS Number: 7689-03-4

Physical and Chemical Properties
Formula: C20H16N2O4
Molecular Weight: 348.36
Solubility: DMSO 3 mg/mL
Storage: 2-8°C, protect from light
Chemical Structure: Camptothecin Structure
Analytical Data
QC Standard: 99.88%
H-NMR: Consistent with structure
Product Information
Description: Camptothecin (CPT), an alkaloid, is an inhibitor of DNA Topoisomerase I (Topo I) with an IC50 value of 679 nM. Camptothecin (CPT) has strong antitumor activity against colorectal cancer, breast cancer, lung cancer and ovarian cancer, and modulates hypoxia-inducible factor-1α (HIF-1α) activity by altering miRNA expression patterns in human cancer cells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.