Certificate of Analysis

 

Catalog Number: M6145
Product Name: BMS-5
CAS Number: 1338247-35-0

Physical and Chemical Properties
Formula: C17H14Cl2F2N4OS
Molecular Weight: 431.29
Solubility: 34 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: BMS-5 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: BMS-5 is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively).Inhibits cofilin phosphorylation in MDA-MB-231 breast cancer cells. Reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.