Certificate of Analysis
| Product Name: | Ac-FLTD-CMK |
| Catalog Number: | M10774 |
| CAS Number: | 2376255-48-8 |
Physical and Chemical Properties
| Formula: | C26H37ClN4O8 |
| Molecular Weight: | 569.05 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: | -20°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Ac-FLTD-CMK is a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |