Certificate of Analysis


Catalog Number: M5303
Product Name: 1-Naphthyl PP1
CAS Number: 221243-82-9

Physical and Chemical Properties
Formula: C19H19N5
Molecular Weight: 317.39
Solubility: 14.25 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: 1-Naphthyl PP1 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: 1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.