Certificate of Analysis

 

Product Name: 1-Naphthyl PP1
Catalog Number: M5303
CAS Number: 221243-82-9

Physical and Chemical Properties
Formula: C19H19N5
Molecular Weight: 317.39
Solubility: DMSO ≥ 10 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: 1-Naphthyl PP1 Structure
Analytical Data
QC Standard: >98.5%
H-NMR: Consistent with structure
Product Information
Description: 1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.