Certificate of Analysis

 

Product Name: ZK824190 hydrochloride 
Catalog Number: M29739
CAS Number: 2629177-12-2

Physical and Chemical Properties
Formula: C22H21ClF2N2O4
Molecular Weight: 450.86
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: 4°C, protect from light
Chemical Structure: ZK824190 hydrochloride  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis. IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.