Certificate of Analysis
| Product Name: | Zileuton |
| Catalog Number: | M2332 |
| CAS Number: | 111406-87-2 |
Physical and Chemical Properties
| Formula: | C11H12N2O2S |
| Molecular Weight: | 236.29 |
| Solubility: | DMSO ≥ 75 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Zileuton is an orally active 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis with IC50 values of 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |