Certificate of Analysis

 

Product Name: CH 5450
Catalog Number: M29691
CAS Number: 252557-97-4

Physical and Chemical Properties
Formula: C34H44N4O9
Molecular Weight: 652.73
Form: Solid
Solubility: DMSO ≥ 43 mg/mL
Storage: Store at ≤ -20°C, dry, sealed
Chemical Structure: CH 5450 Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.