Certificate of Analysis

 

Product Name: YO-01027
Catalog Number: M3523
CAS Number: 209984-56-5

Physical and Chemical Properties
Formula: C26H23F2N3O3
Molecular Weight: 463.48
Solubility: DMSO 83 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: YO-01027 Structure
Analytical Data
QC Standard: 100.00%
H-NMR: Consistent with structure
Product Information
Description: YO-01027 (Dibenzazepine, DBZ) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM for APPL and Notch cleavage, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.