Certificate of Analysis

 

Product Name: YIL781 hydrochloride 
Catalog Number: M28758
CAS Number: 1640226-17-0

Physical and Chemical Properties
Formula: C24H29ClFN3O2
Molecular Weight: 445.96
Form: Solid
Solubility: DMSO 250 mg/mL (ultrasonic)
Storage: -20°C, dry, sealed
Chemical Structure: YIL781 hydrochloride  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 hydrochloride produces a greater improvement in glucose homeostasis in rats. YIL-781 hydrochloride inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.