Certificate of Analysis

 

Product Name: XRD-0394
Catalog Number: M55625
CAS Number: 2595308-10-2

Physical and Chemical Properties
Formula: C26H30FN5O4S
Molecular Weight: 527.61
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: XRD-0394 Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: XRD-0394 is a potent and specific, orally bioavailable dual inhibitor of ATM and DNA-PKcs. XRD-0394 significantly enhanced tumor cell kill in the setting of therapeutic ionizing irradiation in vitro and in vivo. XRD-0394 also potentiates the effectiveness of topoisomerase I inhibitors in vitro.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.