Product Name: | XRD-0394 |
Catalog Number: | M55625 |
CAS Number: | 2595308-10-2 |
Formula: | C26H30FN5O4S |
Molecular Weight: | 527.61 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Chemical Structure: | ![]() |
QC Standard: | |
H-NMR: | Consistent with structure |
Description: | XRD-0394 is a potent and specific, orally bioavailable dual inhibitor of ATM and DNA-PKcs. XRD-0394 significantly enhanced tumor cell kill in the setting of therapeutic ionizing irradiation in vitro and in vivo. XRD-0394 also potentiates the effectiveness of topoisomerase I inhibitors in vitro. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |