Certificate of Analysis

 

Product Name: XL413 hydrochloride
Catalog Number: M13618
CAS Number: 2062200-97-7

Physical and Chemical Properties
Molecular Weight: 326.18
Solubility: Water 10 mg/mL; DMSO 3.4 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: XL413 hydrochloride Structure
Analytical Data
QC Standard: 98.85%
H-NMR: Consistent with structure
Product Information
Description: XL413 (BMS-863233) hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.