Product Name: | WEE1-IN-5 |
Catalog Number: | M49836 |
CAS Number: | 2243882-74-6 |
Formula: | C26H28Cl2N6O |
Molecular Weight: | 511.45 |
Form: | Solid |
Solubility: | DMSO 15 mg/mL (ultrasonic and warming) |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
QC Standard: | ≥98.0% |
H-NMR: | Consistent with structure |
Description: | WEE1-IN-5 is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. WEE1-IN-5 inhibits phospho-CDC2. WEE1-IN-5 abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |