Certificate of Analysis


Product Name: WEE1-IN-5 
Catalog Number: M49836
CAS Number: 2243882-74-6

Physical and Chemical Properties
Formula: C26H28Cl2N6O
Molecular Weight: 511.45
Form: Solid
Solubility: DMSO 15 mg/mL (ultrasonic and warming)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: WEE1-IN-5  Structure
Analytical Data
QC Standard: ≥98.0%
H-NMR: Consistent with structure
Product Information
Description: WEE1-IN-5 is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. WEE1-IN-5 inhibits phospho-CDC2. WEE1-IN-5 abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.