Certificate of Analysis
| Product Name: | VX-745 |
| Catalog Number: | M3294 |
| CAS Number: | 209410-46-8 |
Physical and Chemical Properties
| Formula: | C19H9Cl2F2N3OS |
| Molecular Weight: | 436.26 |
| Solubility: | DMSO 11 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.96% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | VX-745 is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |