Certificate of Analysis

 

Product Name: Vosoritide acetate
Catalog Number: M10742
CAS Number: 1480724-61-5

Physical and Chemical Properties
Formula: C176H290N56O51S3
Molecular Weight: 4102.73
Solubility: Water ≥ 1 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Analytical Data
QC Standard: 99.66%
H-NMR: Consistent with structure
Product Information
Description: Vosoritide (BMN111) is a C-type natriuretic peptide (CNP) analogue that is an endochondral ossification stimulant that binds to specific receptors to initiate intracellular signaling that inhibits the overactive FGFR3 pathway.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.