Certificate of Analysis

 

Product Name: Verubecestat TFA
Catalog Number: M42633
CAS Number: 2095432-65-6

Physical and Chemical Properties
Formula: C19H18F5N5O5S
Molecular Weight: 523.43
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Verubecestat TFA Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: Verubecestat (MK-8931) TFA is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.