Certificate of Analysis

 

Product Name: Vemurafenib-d5
Catalog Number: M21520
CAS Number: 1365986-90-8

Physical and Chemical Properties
Formula: C23H13D5ClF2N3O3S
Molecular Weight: 494.95
Solubility: N/A
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Vemurafenib-d5 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Vemurafenib (PLX4032; RG7204; RO5185426) is a first-in-class selective B-RAF inhibitor that inhibits the activity of RAFV600E and c-RAF-1 with IC50 at 31 nM and 48 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.