Certificate of Analysis
| Product Name: | Valecobulin hydrochloride |
| Catalog Number: | M28021 |
| CAS Number: | 1240321-53-2 |
Physical and Chemical Properties
| Formula: | C26H29ClN6O5S |
| Molecular Weight: | 573.06 |
| Form: | Solid |
| Solubility: | DMSO 125 mg/mL (ultrasonic); Water 50 mg/mL (ultrasonic) |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Valecobulin hydrochloride (CKD-516 hydrochloride) is a valine proagent of S516 and a vascular disrupting agent (VDA). Valecobulin hydrochloride is a potent β-tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |