Certificate of Analysis

 

Product Name: Unecritinib
Catalog Number: M45163
CAS Number: 1418026-92-2

Physical and Chemical Properties
Formula: C23H24Cl2FN5O2
Molecular Weight: 492.37
Solubility: DMSO 100 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Unecritinib Structure
Analytical Data
QC Standard: >98.5%
H-NMR: Consistent with structure
Product Information
Description: Unecritinib is a potent EGFR tyrosine kinase inhibitor that inhibits ALK, ROS1, and MET and has anticancer activity. Unecritinib is indicated for use in studies of solid tumors and ALK-positive anaplastic large cell lymphoma.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.