Certificate of Analysis

 

Product Name: Umibecestat
Catalog Number: M28304
CAS Number: 1387560-01-1

Physical and Chemical Properties
Formula: C19H15ClF7N5O2
Molecular Weight: 513.8
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: 4°C, protect from light
Chemical Structure: Umibecestat Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Umibecestat (CNP520) is a beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) inhibitor with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer's disease.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.