Product Name: | Umbralisib hydrochloride |
Catalog Number: | M14858 |
CAS Number: | 1532533-78-0 |
Molecular Weight: | 608.01 |
Solubility: | DMSO ≥ 100 mg/mL |
Storage: | 2-8°C, dry, sealed |
Chemical Structure: |
QC Standard: | >99% |
H-NMR: | Consistent with structure |
Description: | Umbralisib hydrochloride (TGR-1202 hydrochloride) is a novel PI3Kδ inhibitor, with IC50 and EC50 of 22.2 nM and 24.3 nM, respectively; Umbralisib hydrochloride (TGR-1202 hydrochloride) is also active against CK1ε, with an EC50 value of 6.0 μM. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |