Certificate of Analysis
| Product Name: | UK-78282 monohydrochloride |
| Catalog Number: | M8837 |
| CAS Number: | 136647-02-4 |
Physical and Chemical Properties
| Formula: | C29H35NO2HCl |
| Molecular Weight: | 466.05 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: | -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | UK-78282 is a novel, potent and selective Kv1.3 blocker with an IC50 of 200 nM. UK-78282 effectively suppresses human T-lymphocyte activation in vitro. UK-78282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |