Certificate of Analysis
| Product Name: | Trovafloxacin |
| Catalog Number: | M28511 |
| CAS Number: | 147059-72-1 |
Physical and Chemical Properties
| Formula: | C20H15F3N4O3 |
| Molecular Weight: | 416.35 |
| Form: | Solid |
| Solubility: | DMSO 10 mg/mL (ultrasonic and adjust pH to 4 with HCl) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |