Certificate of Analysis
| Product Name: | Trimetazidine dihydrochloride |
| Catalog Number: | M6037 |
| CAS Number: | 13171-25-0 |
Physical and Chemical Properties
| Formula: | C14H22N2O3.2HCl |
| Molecular Weight: | 339.26 |
| Solubility: | Water 67 mg/mL; DMSO 20 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.74% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |