Certificate of Analysis
| Product Name: | TPX-0131 |
| Catalog Number: | M14147 |
| CAS Number: | 2648641-36-3 |
Physical and Chemical Properties
| Formula: | C21H20F3N5O3 |
| Molecular Weight: | 447.41 |
| Solubility: | DMSO : 25 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >95% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | The CNS-penetrant ALK kinase inhibitor TPX-0131 was more potent in vitro against WT-ALK and many ALK resistance mutations than all five approved ALK inhibitors. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |