Certificate of Analysis


Product Name: Topotecan hydrochloride
Catalog Number: M2144
CAS Number: 119413-54-6

Physical and Chemical Properties
Formula: C23H23N3O5.HCl
Molecular Weight: 457.91
Solubility: DMSO 35 mg/mL; Water 33 mg/mL
Storage: 2-8°C, protect from light, sealed
Chemical Structure: Topotecan hydrochloride Structure
Analytical Data
QC Standard: 98.91%
H-NMR: Consistent with structure
Product Information
Description: Topotecan hydrochloride is a topoisomerase I inhibitor and an apoptosis inducer.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.