Certificate of Analysis

 

Catalog Number: M3616
Product Name: Tofacitinib citrate
CAS Number: 540737-29-9

Physical and Chemical Properties
Formula: C22H28N6O8
Molecular Weight: 504.49
Solubility: DMSO >30 mg/mL, Water 2 mg/mL
Storage: at -20°C
Chemical Structure: Tofacitinib citrate  Structure
Analytical Data
HPLC: Shows Min 98.93% purity
H-NMR: Consistent with structure
Product Information
Description: Tofacitinib (CP-690550) Citrate is a novel inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent against JAK2 and JAK1.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.