Certificate of Analysis

 

Product Name: THZ1
Catalog Number: M5228
CAS Number: 1604810-83-4

Physical and Chemical Properties
Formula: C31H28ClN7O2
Molecular Weight: 566.05
Solubility: DMSO: ≥ 25 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: THZ1 Structure
Analytical Data
QC Standard: 98.33%
H-NMR: Consistent with structure
Product Information
Description: THZ1 is a covalent CDK7 inhibitor which has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.