Certificate of Analysis
| Product Name: | Thyroid hormone receptor antagonist (1-850) |
| Catalog Number: | M58468 |
| CAS Number: | 251310-57-3 |
Physical and Chemical Properties
| Formula: | C21H20F3N5O4 |
| Molecular Weight: | 463.41 |
| Form: | Crystalline Solid |
| Storage: | Store at -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Thyroid hormone receptor antagonist (1-850) is a competitive, selective and high-affinity thyroid hormone receptor (TR) antagonist with an IC50 of 1.5 μM for antagonizing the effect of T3 on TR. Thyroid hormone receptor antagonist (1-850) blocks T3-mediated interaction of TRα and TRβ with nuclear receptor coactivator. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |