Certificate of Analysis

 

Product Name: TH1834 dihydrochloride 
Catalog Number: M29245
CAS Number: 2108830-09-5

Physical and Chemical Properties
Formula: C33H42Cl2N6O3
Molecular Weight: 641.63
Form: Solid
Solubility: Water 100 mg/mL (ultrasonic); DMSO ≥ 100 mg/mL
Storage: 4°C, dry, sealed
Chemical Structure: TH1834 dihydrochloride  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: TH1834 dihydrochloride is a specific Tip60 (KAT5) histone acetyltransferase inhibitor. TH1834 dihydrochloride induces apoptosis and increases DNA damage in breast cancer. TH1834 dihydrochloride does not affect the activity of related histone acetyltransferase MOF. Anticancer activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.