Product Name:	Tesevatinib
Catalog Number:	M14143
CAS Number:	781613-23-8

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Physical and Chemical Properties

Molecular Weight:	491.39
Solubility:	DMSO 90 mg/mL
Storage:	Powder          -20°C   3 years ;  4°C   2 years In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure:

Analytical Data

QC Standard:	>99%
H-NMR:	Consistent with structure

Product Information

Description:	Tesevatinib (XL-647; EXEL-7647; KD-019) is an orally available, multi-target tyrosine kinase inhibitor; inhibits EGFR, ErbB2, KDR, Flt4 and EphB4 kinase with IC50s of 0.3, 16, 1.5, 8.7, and 1.4 nM.
Stability and Solubility Advice:	Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.

AbMole BioScience

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