Certificate of Analysis
| Product Name: | Tepoditamab |
| Catalog Number: | M24886 |
| CAS Number: | 2044679-53-8 |
Physical and Chemical Properties
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Analytical Data
| QC Standard: | |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Tepoditamab (MCLA-117) is a bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab (MCLA-117) kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells and can be used in acute myeloid leukaemia (AML) research. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |