Certificate of Analysis
| Product Name: | TCS JNK 6o |
| Catalog Number: | M7395 |
| CAS Number: | 894804-07-0 |
Physical and Chemical Properties
| Formula: | C18H20N4O4 |
| Molecular Weight: | 356.38 |
| Form: | Solid |
| Solubility: | DMSO 35.64 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | TCS JNK 6o is a aTP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively). TCS JNK 6o displays > 1000 fold selectivity over other kinases, including ERK2 and p38. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |