Certificate of Analysis
| Product Name: | TCMDC-135051 |
| Catalog Number: | M21393 |
| CAS Number: | 2413716-15-9 |
Physical and Chemical Properties
| Formula: | C29H33N3O3 |
| Molecular Weight: | 471.59 |
| Solubility: | DMSO ≥ 200 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ＞98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | TCMDC-135051 is a highly selective and potent inhibitor of the protein kinase PfCLK3 with low off-target toxicity.TCMDC-135051 prevents trophozoite to lytic transition, disrupts transcription and reduces transmission to mosquito vectors.TCMDC-135051 has antiparasitic activity (EC50=320 nM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |