Certificate of Analysis
| Product Name: | TAT-cyclo-CLLFVY TFA |
| Catalog Number: | M31057 |
Physical and Chemical Properties
| Formula: | C113H189F3N42O26S2 |
| Molecular Weight: | 2673.1 |
| Solubility: | Water |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Analytical Data
| QC Standard: | ≥99.0% |
Product Information
| Description: | TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY TFA disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |