Certificate of Analysis
| Product Name: | TAS4464 hydrochloride |
| Catalog Number: | M14478 |
| CAS Number: | 1848959-11-4 |
Physical and Chemical Properties
| Molecular Weight: | 542.97 |
| Solubility: | DMSO 83.33 mg/mL; Water 5 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | 2-8°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |