Certificate of Analysis
| Product Name: | Tafamidis |
| Catalog Number: | M4847 |
| CAS Number: | 594839-88-0 |
Physical and Chemical Properties
| Formula: | C14H7Cl2NO3 |
| Molecular Weight: | 308.12 |
| Solubility: | DMSO 38 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.00% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade, with EC50s of 2.7-3.2 μM to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |