Certificate of Analysis
| Product Name: | SY-5609 |
| Catalog Number: | M10966 |
| CAS Number: | 2417302-07-7 |
Physical and Chemical Properties
| Formula: | C23H26F3N6OP |
| Molecular Weight: | 490.46 |
| Solubility: | DMSO ≥ 30 mg/mL |
| Storage: | 4°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |