Certificate of Analysis

 

Product Name: SW044248
Catalog Number: M8640
CAS Number: 522650-83-5

Physical and Chemical Properties
Formula: C22H23N5O2S
Molecular Weight: 421.52
Form: Solid
Solubility: DMSO: 5 mg/mL (warmed)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SW044248 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: SW044248 is a cell permeable, indolotriazine-based compound that selectively inhibits topoisomerase 1 (Top 1), but not Top 2, catalyzed DNA decatenation in a manner distinct from that of camptothecin (Cat.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.