Certificate of Analysis

 

Product Name: SU16f 
Catalog Number: M29685
CAS Number: 251356-45-3

Physical and Chemical Properties
Formula: C24H22N2O3
Molecular Weight: 386.44
Form: Solid
Solubility: DMSO 50 mg/mL (ultrasonic)
Storage: Powder -20°C
Chemical Structure: SU16f  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: SU16f is a potent and selective PDGFRβ inhibitor with IC50s of 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively. Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.