Certificate of Analysis
| Product Name: | SPD304 |
| Catalog Number: | M10950 |
| CAS Number: | 869998-49-2 |
Physical and Chemical Properties
| Formula: | C32H32F3N3O2 |
| Molecular Weight: | 547.61 |
| Solubility: | DMSO ≥ 20 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SPD304 is a selective inhibitor of tumor necrosis factor α (TNF-α) that promotes the separation of tumor necrosis factor trimers, thereby blocking their interaction with receptors. SPD304 inhibits tumor necrosis factor in vitro α and receptor 1 binding IC50 The value is 22 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |