Product Name: | SPA70 |
Catalog Number: | M30932 |
CAS Number: | 931314-31-7 |
Formula: | C21H25N3O4S |
Molecular Weight: | 415.51 |
Form: | Solid |
Solubility: | DMSO 40 mg/mL (Need ultrasonic and warming) |
Storage: | Powder -20°C |
Chemical Structure: | ![]() |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | SPA70 is a potent and selective antagonist of human pregnane X receptor (hPXR), with an IC50 of 540 nM (Ki=390 nM). SPA70 can enhance the chemosensitivity of cancer cells. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |