Certificate of Analysis

 

Product Name: SPA70 
Catalog Number: M30932
CAS Number: 931314-31-7

Physical and Chemical Properties
Formula: C21H25N3O4S
Molecular Weight: 415.51
Form: Solid
Solubility: DMSO 40 mg/mL (Need ultrasonic and warming)
Storage: Powder -20°C
Chemical Structure: SPA70  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: SPA70 is a potent and selective antagonist of human pregnane X receptor (hPXR), with an IC50 of 540 nM (Ki=390 nM). SPA70 can enhance the chemosensitivity of cancer cells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.