Certificate of Analysis

 

Product Name: Soquelitinib
Catalog Number: M58440
CAS Number: 2226636-04-8

Physical and Chemical Properties
Formula: C25H30N4O4S2
Molecular Weight: 514.66
Solubility: DMSO ≥ 80 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Soquelitinib Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease. Soquelitinib increases tumor infiltration of normal CD8+ cells that possess enhanced T effector function.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.