Certificate of Analysis
| Product Name: | SKPin C1 |
| Catalog Number: | M7305 |
| CAS Number: | 432001-69-9 |
Physical and Chemical Properties
| Formula: | C18H13BrN2O4S2 |
| Molecular Weight: | 465.34 |
| Solubility: | DMSO 4.65 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SKPin C1 is a inhibitor of Skp2-mediated p27 degradation. SKPin C1 induces p27 accumulation in metastatic melanoma cell lines. SKPin C1 promotes G1/S cell cycle arrest in T47D cells and LNCaP cells. SKPin C1 induces G2/M cell cycle arrest in MCF-7 cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |