Certificate of Analysis
| Product Name: | SK-575 |
| Catalog Number: | M29689 |
| CAS Number: | 2523016-96-6 |
Physical and Chemical Properties
| Formula: | C47H53FN8O8 |
| Molecular Weight: | 876.97 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic) |
| Storage: | -20°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1, with an IC50 of 2.30 nM. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |