Certificate of Analysis


Product Name: Sivelestat
Catalog Number: M9550
CAS Number: 127373-66-4

Physical and Chemical Properties
Formula: C20H22N2O7S
Molecular Weight: 434.46
Solubility: DMSO ≥ 50 mg/mL
Storage: 2-8°C, dry, protect from light, sealed
Chemical Structure: Sivelestat Structure
Analytical Data
HPLC: Shows Min >98.5% purity
H-NMR: Consistent with structure
Product Information
Description: Sivelestat (ONO5046; LY544349; EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.