Certificate of Analysis
| Product Name: | Sitagliptin phosphate monohydrate |
| Catalog Number: | M1967 |
| CAS Number: | 654671-77-9 |
Physical and Chemical Properties
| Formula: | C16H15F6N5O.H3PO4.H2O |
| Molecular Weight: | 523.32 |
| Solubility: | Water 41 mg/mL; DMSO 60 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Sitagliptin phosphate (MK-0431) is a potent inhibitor of dipeptidyl peptidase-4 (DPP-4) with IC50 of 19 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |