Product Name: | SIS3 HCl |
Catalog Number: | M8149 |
CAS Number: | 521984-48-5 |
Formula: | C28H27N3O3.HCl |
Molecular Weight: | 489.99 |
Solubility: | DMSO: ≥ 70 mg/mL |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
HPLC: | Shows Min 99.53% purity |
H-NMR: | Consistent with structure |
Description: | SIS3 is a novel specific inhibitor of TGF-β1/ALK-5 phosphorylation of Smad3 with an IC50 of 3 µM. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |