Certificate of Analysis
| Product Name: | SHP099 |
| Catalog Number: | M6314 |
| CAS Number: | 1801747-42-1 |
Physical and Chemical Properties
| Formula: | C16H19Cl2N5 |
| Molecular Weight: | 352.26 |
| Solubility: | DMSO: ≥ 8 mg/mL (Need ultrasonic and warming) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.52% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |