Certificate of Analysis

 

Product Name: SB-633825
Catalog Number: M14766
CAS Number: 956613-01-7

Physical and Chemical Properties
Molecular Weight: 483.58
Solubility: DMSO 9.62 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SB-633825 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.